Just accepted for publication. Bile acid activated receptors and their role in immunity, inflammation and metabolism. Three articles published in : Biochemical Pharmacology Current Opinion in Pharmacology BBA Lipid Press release April 27, 2020
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity Michele Biagioli,* Adriana Carino,* Chiara Fiorucci,* Silvia Marchiano`,*Cristina di Giorgio,* Martina Bordoni,* Rosalinda Roselli,† Monia Baldoni,‡Eleonora Distrutti,x Angela Zampella, and Stefano Fiorucci* *Dipartimento di Scienze Biomediche e Chirurgiche, Universita` di Perugia, Perugia, Italy; † Dipartimento di Farmacia,
Precision Bio Therapeutics is a Spin Off of The University of Perugia generated by a collaboration between pharma companies and academics to boost drug development on novel targets for gastrointestinal and liver diseases. Work is in progres. Precision
Just accepted for publication- FASEB J 2018 Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steato-hepatitis Adriana Carino1, Silvia Marchianò1, Michele Biagioli1, Mariarosaria Bucci2, Valentina Vellecco2, Vincenzo Brancaleone3, Chiara Fiorucci1, Angela Zampella2, Maria Chiara Monti4, Eleonora Distrutti5 and Stefano Fiorucci1*
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