Journal of Immunology 2020-Just accepted for publication. A study from prof. Fiorucci’s lab at University of Perugia illustrates a novel approach for treating acute liver failure in model of acethaminophen (paracetamol) intoxication
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity Michele Biagioli,* Adriana Carino,* Chiara Fiorucci,* Silvia Marchiano`,*Cristina di Giorgio,* Martina Bordoni,* Rosalinda Roselli,† Monia Baldoni,‡Eleonora Distrutti,x Angela Zampella, and Stefano Fiorucci* *Dipartimento di Scienze Biomediche e Chirurgiche, Universita` di Perugia, Perugia, Italy; † Dipartimento di Farmacia,