Gastroenterologia Perugia – Coord. Prof. Stefano Fiorucci

- 11 NOV 24
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Management delle emorragie digestive 9/12/2024
ADE 2024- Emorragie
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- 27 SET 24
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Top 2% World Scientists 2024- The Fiorucci’s lab at the University of Perugia ranks 6 researchers in the list
Sei ricercatori del Laboratorio di Gastroenterologia Diretto dal Prof. Stefano Fiorucci Università degli Studi di Perugia, sono inclusi nella lista dei top scientists 2024: Prof. Stefano Fiorucci (per la quinta volta in 5 anni) Dr.ssa Eleonora Distrutti Dr. Michele Biagioli Dr.ssa Adriana Carino (past member) Barbara Renga (past member) Andrea Mencarelli (currently in China)
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- 15 SET 24
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Discovery of a Novel Therapeutic Agent for IBD. A dual ligand acting on two bile acid acid regulated receptors:RORγT and GPBAR1
Pharmacological Research, Just published Prof. Stefano Fiorucci’s laboratory University of Perugia reports the discovery of a novel RORγT/GPBAR1 ligand for IBD
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- 02 SET 24
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Prof. Stefano Fiorucci- Progetti PNRR 2024 -Nanocarriers development for treating fibrotic disorders
Nanocarriers for fibrotic disorders-Università degli Studi di Perugia-Prof. Stefano Fiorucci FIORUCCI PNRR progetti nazionali
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- 08 MAR 24
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Recently Published Hepatology 2023 Jul 1;78(1):26-44
Hepatology 2023 Jul 1;78(1):26-44. doi: 10.1002/hep.32787. Epub 2022 Oct 12. Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury Michele Biagioli 1, Silvia Marchianò 1, Cristina di Giorgio 1, Rosalinda Roselli 2, Martina Bordoni 1, Rachele Bellini 1,
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- 06 MAR 24
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FXR and GPBAR1 signaling in the vascular system and liver in MASLD. A recent study published by JAHA 2023 highlights a role of bile acids in liver steatohepatitis and atherosclerosis
Vascular injury linked to metabolic dysfunction-associated steatotic liver disease (MASLD) By Stefano Fiorucci, MD and others Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G‐Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease Silvia Marchianò, Michele Biagioli, Martina Bordoni, Elva Morretta, Cristina Di
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- 06 MAR 24
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Recently published- Bile acids and COVID19. From a gastroenterology and hepatology perspective. Biochem Pharmacology December 2023
A review article by prof. Stefano Fiorucci and its group on bile acids and COVID19. Pathogenetic and therapeutic implications. Bile acids and COVID19
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- 19 MAR 22
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Just accepted for publication- Fiorucci S., et al- Novel dual CystLTR1 antagonist/GPBAR1 agonist effectively reverses liver steatosis- Frontiers in Pharmacology 2022
Precision Biotherapeutics SrL a Spinoff of the University of Perugia reports new preclinical data on its lead compound CHIN117 on liver steatosis CysLTR1-GPBAR1 agonist
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Prof. Stefano Fiorucci

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Management delle emorragie digestive 9/12/2024

Top 2% World Scientists 2024- The Fiorucci’s lab at the University of Perugia ranks 6 researchers in the list

Discovery of a Novel Therapeutic Agent for IBD. A dual ligand acting on two bile acid acid regulated receptors:RORγT and GPBAR1

Prof. Stefano Fiorucci- Progetti PNRR 2024 -Nanocarriers development for treating fibrotic disorders

Recently Published Hepatology 2023 Jul 1;78(1):26-44

FXR and GPBAR1 signaling in the vascular system and liver in MASLD. A recent study published by JAHA 2023 highlights a role of bile acids in liver steatohepatitis and atherosclerosis

Recently published- Bile acids and COVID19. From a gastroenterology and hepatology perspective. Biochem Pharmacology December 2023

Just accepted for publication- Fiorucci S., et al- Novel dual CystLTR1 antagonist/GPBAR1 agonist effectively reverses liver steatosis- Frontiers in Pharmacology 2022

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